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Welcome!

The Nucleus Distribution is an open source package for synthetic cell builders maintained by b.next. The Distribution includes integrated digital tools, biological materials, documentation, and validated protocols for the full process of cell building, including cytosol construction, DNA content engineering, and membrane encapsulation.

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What’s new in v0.4.0

Open science

The sixth stable release of the Nucleus Distribution (v0.4.0) is now available. The Distribution is supported by the Astera Institute, Sloan Foundation, and Caltech.

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PURE Cell

Detector Cells

Emitter Cells

Responder Cells

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Container Documentation

Container Protocols

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Cytosol Documentation

PURE Protocols

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Modules

DNA Distribution

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Guides

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User guides for Nucleus Hub and Nucleus Developer Notes live here:

Making Synthetic Cells for Beginners

Nucleus Hub

Developer Notes

<aside> <img src="/icons/code_gray.svg" alt="/icons/code_gray.svg" width="40px" /> Development

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